Bryan Murray was born and raised in Long Beach, California, served in the Japan Sendai mission, and met his future wife, Kristine Clawson, while attending Brigham Young University when they went skiing together with their home evening group. Bryan attended medical school at the University of Kentucky then completed an internal medicine residency with the UCSF San Joaquin Valley Program. He worked with a small group practice in Payson, Utah, before moving the family to Anacortes, Washington, where he joined a small internal medicine group and helped start a hospitalist program at Island Hospital in Anacortes.